Cxcl12-iCreERT2 Bacterial Artificial Chromosome Transgenic Mice
TECHNOLOGY NUMBER: 2021-377
Technology No. 2021-377
![MOUSE MOUSE](https://storage.googleapis.com/elucid3-storage-1-us/uw/product/10602/cxcl12-icreert2-bacterial-artificial-chromosome-transgenic-mice-01.jpg?mtime=20240726193319?mtime=20240726193319)
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INNOVATION
Cxcl12-creER transgenic mice express a tamoxifen-inducible (ERT2) codon-improved iCre recombinase directed by mouse Cxcl12 (chemokine (C-X-C motif) ligand 12) promoter elements. When induced, iCre recombinase activity is observed in a subset of bone marrow stromal cells. This strain may be useful for in vivo lineage tracing and functional analysis of skeletal regeneration and a pre-adipocyte-like subset of bone marrow stromal cells.