Expression Clone of Mocr-UTX

TECHNOLOGY NUMBER: 4634
Technology No. 4634
HISTONE
1

INNOVATION

Our goal was to construct variants from a number of genes that will allow for biochemical characterization as well as structural studies. All the target genes are from two families that contain the JmjC domain and are thought to be histone demethylases. One gene, UTX, is a human histone H3 Lys27-specific demetylase. UTX has been shown to be essential for normal development. It has also been linked to human cancers and is thought to act as a tumor suppressor.

 

ADDITIONAL DETAILS

Cayman Chemical https://www.caymanchem.com/product/10774/utx-(human%2C-recombinant)

  • swap_vertical_circlemode_editInventor (2)
    Raymond Trievel
    William Brown
  • swap_vertical_circlecloud_downloadSupporting documents (1)
    Product brochure
    Expression Clone of Mocr-UTX.pdf
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