Mouse Models for Hematological Research and Plasminogen Activation (F5 Leiden mutation)

TECHNOLOGY NUMBER: 2015-516
Technology No. 2015-516
MOUSE
1

INNOVATION

These mice carry the F5 Leiden mutation whereby the arginine at position 504 is replaced by a glutamine disrupting a cleavage site necessary for the inactivation of the factor V protein. These F5 Leiden mutation mice serve as a model for blood coagulation defects.

 

ADDITIONAL DETAILS

Jackson https://www.jax.org/strain/004080

  • swap_vertical_circlemode_editInventor (1)
    David Ginsburg
  • swap_vertical_circlecloud_downloadSupporting documents (1)
    Product brochure
    Mouse Models for Hematological Research and Plasminogen Activation (F5 Leiden mutation).pdf
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