Mouse Models for Immunology, Inflammation, and Autoimmunity Research (18 COX-2)

INNOVATION

These Δ18 COX-2 mice express a mutant prostaglandin endoperoxide H synthase-2 with an 18-amino acid deletion in exon 10 that prevents the protein's entry into the endoplasmic reticulum-associated protein degradation (ERAD) system.

 

ADDITIONAL DETAILS

Jackson https://www.jax.org/strain/027210