AR113Q Knock-In Mice
TECHNOLOGY NUMBER: 2019-197
Technology No. 2019-197
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OVERVIEW
This mouse line has the mouse androgen receptor gene exon 1 swapped with the human androgen receptor gene exon 1. Males of this line develop an androgen-dependent phenotype characterized by decreased body weight, weakness, testicular atrophy and early death. This mouse is a model of androgen dependence.