AR113Q Knock-In Mice

TECHNOLOGY NUMBER: 2019-197
Technology No. 2019-197
MOUSE
1

OVERVIEW

This mouse line has the mouse androgen receptor gene exon 1 swapped with the human androgen receptor gene exon 1. Males of this line develop an androgen-dependent phenotype characterized by decreased body weight, weakness, testicular atrophy and early death. This mouse is a model of androgen dependence.


  • swap_vertical_circlemode_editAuthors (2)
    Andrew Lieberman
    Diane Robins
  • swap_vertical_circlecloud_downloadSupporting documents (0)
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