Mouse Models for Developmental Biology Research (TERTfl)
TECHNOLOGY NUMBER: 2015-495
Technology No. 2015-495
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INNOVATION
TERTfl/fl mice possess loxP sites flanking exons 1-2 of the telomerase reverse transcriptase (Tert) gene making them useful for tissue specific TERT deficiency. These floxed mice are useful when studying cancer, aging, senescence, injury/wound healing, stress, diabetes, and rare human diseases including aplastic anemia and Dyskeratosis congenita.