Mouse Models for Immunology, Inflammation, and Autoimmunity Research (Fut7/Fut4 knock-out)

INNOVATION

In this strain the catalytic domains of the fucosyltransferase 4 (Fut4) gene and the fucosyltransferase 7 (Fut7) gene were replaced with neomycin resistance (neo) cassettes, abolishing gene function. These mice may be useful for studying leukocyte recruitment and lymphocyte homing.

ADDITIONAL DETAILS