Mouse Models for Internal/Organ and Bone Research (12.4KVil-EGFP)
TECHNOLOGY NUMBER: 2015-498
Technology No. 2015-498
1
INNOVATION
12.4KVil-EGFP transgenic mice have the 12.4 kbp mouse villin 1 promoter directing expression of EGFP to villus and crypt epithelial cells, along the entire small intestine and colon, in a cephalocaudal gradient expression pattern similar to endogenous Vil1. These mice may be useful in studying intestinal organogenesis, gastric stem cell biology and cancer.