p75 Conditional Knockout Mouse

INNOVATION

This is a transgenic mouse that allows for the deletion of the receptor p75 when crossed with other mice that express Cre recombinase. LoxP sites were placed around exons 4,5 and 6 of the p75 gene. The p75floxed mice have the great advantage over existing germline Ret knockout mice in that you can control when and where p75 is deleted.